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Co-op Student, Bioconjugation

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Zymeworks Inc.

May 14

Applications are closed

  • Internship
    Full-time
    Off-cycle Internship
  • Research & Development
    Science
  • Vancouver

Requirements

  • Currently enrolled in an undergraduate program in Biology, Biochemistry, Chemistry, Immunology or a related discipline and successful completion of at least one relevant co-op term are required. Availability for an 8 month co-op term is also required.
  • Skills and Abilities:
  • Proven interpersonal skills with the ability to work collaboratively as a member of cross-functional team. Ability to establish and maintain effective working relationships
  • Good organizational skills and the ability to work effectively in a high paced, fast changing environment. Results-oriented
  • Experience working with antibodies or bioconjugation would be an asset
  • Experience with automated systems and liquid handlers would be an asset
  • Experience involving mammalian tissue culture, FACS, SDS-PAGE, protein purification and quantification, ELISA, or HPLC would be an asset
  • Excellent oral and written communication capabilities
  • Good computer skills particularly with Excel and PowerPoint
  • Basic working knowledge of antibody structure and function

Responsibilities

  • Performs bioconjugation experiments to attach small molecules to antibodies and other proteins
  • Characterizes antibodies and antibody-drug conjugates using HPLC-HIC, HPLC-SEC, SDS-PAGE, CE-SDS, flow cytometry and other methods as required
  • Assists with functional characterization of bioconjugates using, for example, cell growth inhibition assays
  • Performs experiments, interprets and analyzes data, and prepares presentations for group meetings
  • Conducts all activities in accordance with scientific standards, OS&H regulations and established Zymeworks’ policies and practices
  • Adheres to Zymeworks standard procedures for generating, documenting and archiving data, maintaining an accurate, up-to-date lab notebook or electronic notebook
  • Contributes to a safe and highly efficient laboratory environment through ordering of consumables, preparation of solutions, stocking of consumables, and maintaining a clean working environment
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Zymeworks Inc.

Developing novel medicines for patients with difficult-to-treat cancers and other serious diseases.

Science & Healthcare
Industry
201-500
Employees
2003
Founded Year

Mission & Purpose

Zymeworks (NASDAQ:ZYME) is a clinical-stage biopharmaceutical company dedicated to the development of next-generation multifunctional biotherapeutics. Zymeworks’ suite of therapeutic platforms and its fully integrated drug development engine enable precise engineering of highly differentiated product candidates. Zymeworks’ lead clinical candidate, zanidatamab, is a novel Azymetric™ HER2-targeted bispecific antibody currently being evaluated in multiple Phase 1, Phase 2, and pivotal clinical trials globally as a targeted treatment option for patients with solid tumors that express HER2. Zymeworks’ second product candidate, Zanidatamab Zovodotin (ZW49), is a bispecific antibody-drug conjugate currently in Phase 1 clinical development and combines the unique design and antibody framework of zanidatamab with Zymeworks’ proprietary ZymeLink™ linker-cytotoxin. Zymeworks is also advancing a deep preclinical pipeline in oncology (including immuno-oncology agents) and other therapeutic areas. In addition, its therapeutic platforms are being leveraged through strategic partnerships with nine biopharmaceutical companies.