Co-op Student, In Vitro Biology

Zymeworks Inc.

2mo ago

Applications are closed

Internship
Full-time
Off-cycle Internship
Research & Development
Science
Vancouver

Requirements

Currently enrolled in an undergraduate program in Biology, Biochemistry, Chemistry, Immunology or a related discipline, and successful completion of at least one relevant co-op term is required. Availability for an 8-month co-op term is also required.
Skills and Abilities:
Experience involving mammalian tissue culture, flow cytometry, fluorescence imaging, SDS-PAGE, protein purification and quantification, ELISA, or HPLC would be an asset.
Good organizational skills and the ability to work effectively in a high paced, fast changing environment.
Proven interpersonal skills with the ability to work collaboratively as a member of cross-functional team.
Good oral and written communication skills.
Good computer skills particularly with Excel and PowerPoint. Experience with or knowledge of GraphPad Prism and FlowJo software are considered an asset.
Basic working knowledge of antibody structure and function.

Responsibilities

Supports and performs mammalian tissue culture, maintaining numerous tumor cell lines using sterile technique.
Works with team to ensure cell lines are properly expanded, cryopreserved, and databases updated as required.
Performs functional characterization of antibodies and ADCs using flow cytometry, high throughput screening, 3D tissue culture, cell growth inhibition assays with various read-out modalities (luminescence, fluorescence, absorbance), and other methods as required.
Performs experiments, analyzes and disseminates data in group meetings.
Adheres to Zymeworks standard procedures for generating, documenting, and archiving data, maintaining an accurate, up-to-date electronic laboratory notebook.
Conducts all activities in accordance with scientific standards, OS&H regulations and established Zymeworks policies and practices.
Contributes to a safe and highly efficient laboratory environment through ordering of consumables, preparation of solutions, stocking of consumables, and maintaining a clean working environment.

Zymeworks Inc.

Developing novel medicines for patients with difficult-to-treat cancers and other serious diseases.

Science & Healthcare

Industry

201-500

Employees

2003

Founded Year

Mission & Purpose

Zymeworks (NASDAQ:ZYME) is a clinical-stage biopharmaceutical company dedicated to the development of next-generation multifunctional biotherapeutics. Zymeworks’ suite of therapeutic platforms and its fully integrated drug development engine enable precise engineering of highly differentiated product candidates. Zymeworks’ lead clinical candidate, zanidatamab, is a novel Azymetric™ HER2-targeted bispecific antibody currently being evaluated in multiple Phase 1, Phase 2, and pivotal clinical trials globally as a targeted treatment option for patients with solid tumors that express HER2. Zymeworks’ second product candidate, Zanidatamab Zovodotin (ZW49), is a bispecific antibody-drug conjugate currently in Phase 1 clinical development and combines the unique design and antibody framework of zanidatamab with Zymeworks’ proprietary ZymeLink™ linker-cytotoxin. Zymeworks is also advancing a deep preclinical pipeline in oncology (including immuno-oncology agents) and other therapeutic areas. In addition, its therapeutic platforms are being leveraged through strategic partnerships with nine biopharmaceutical companies.