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Co-op Student, Medicinal Chemistry

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Zymeworks Inc.


7d ago

🚀 Off-cycle Internship


AI generated summary

  • You must be enrolled in Chemistry program, completed Organic Chemistry with lab, available for 8-month term, have experience with synthetic chemistry, NMR, HPLC-MS, good communication and computer skills.
  • You will participate in drug synthesis, purification, and characterization, contributing to antibody-drug conjugate platform technology development. Other duties include data analysis, inventory management, and maintaining a safe lab environment.

Off-cycle Internship

Research & Development, Science•Vancouver


  • We are currently seeking a co-op student to join the Medicinal Chemistry team. The successful candidate will be responsible for supporting the generation of target molecules through synthetic chemistry. The successful co-op student will frequently be challenged to critically analyze results and contribute to the Zymeworks team effort to create best-in-class therapeutics. This position reports to a Scientist in the Medicinal Chemistry group and will be based in Vancouver, BC.


  • Education and Experience:
  • Currently enrolled in an undergraduate program in Chemistry and successful completion of Organic Chemistry courses (2nd Year) with lab.
  • Availability for an 8-month co-op term is required.
  • Experience with multi-step synthetic chemistry over and above the teaching lab is preferred
  • Skills and Abilities:
  • Proven interpersonal skills with the ability to work collaboratively as a member of cross-functional team. Ability to establish and maintain effective working relationships
  • Good organizational skills and the ability to work effectively in a high-paced, fast-changing environment. Results-oriented mindset
  • Experience with multi-step synthetic chemistry over and above the teaching lab is required
  • Experience with characterization of small molecules using NMR and HPLC-MS and some familiarity with operating these instruments outside of the teaching lab is preferred.
  • Excellent oral and written communication capabilities
  • Good computer skills particularly with MS Office suite and ChemOffice (ChemDraw)

Education requirements

Currently Studying

Area of Responsibilities

Research & Development


  • The student is expected to participate in the generation of new drugs and drug-linkers for evaluation as potential antibody-drug conjugate platform technologies:
  • Reproduces or adapts established synthetic procedures to transform chemical species into target payloads, intermediates, and drug-linkers
  • Monitors reaction progress using HPLC-MS and TLC
  • Uses appropriate purification techniques (wet work-up, flash chromatography, prep-HPLC-MS) to isolate desired chemical products
  • Characterizes isolated materials to confirm structure and purity (NMR, HPLC-MS)
  • Performs experiments, interprets, and analyzes data, and prepares presentations for group meetings
  • Administrative duties such as contributing to the chemical inventory system
  • Conducts all activities in accordance with scientific standards, OS&H regulations and established Zymeworks policies and practices
  • Adheres to Zymeworks standard procedures for generating, documenting, and archiving data, maintaining an accurate, up-to-date electronic notebook
  • Contributes to a safe and highly efficient laboratory environment through ordering of consumables, regular maintenance of reagent inventory, preparation of solutions, stocking of consumables, and maintaining a clean working environment


Work type

Full time

Work mode