Postdoctoral Researcher – Machine Learning for Protein Design and Engineering

National Renewable Energy Laboratory

Mar 27

Job
Full-time
Entry Level
Research & Development
Data
$73.2K - $120.8K
Golden
Quick Apply

AI generated summary

You must be a recent PhD graduate with research experience in machine learning, bioinformatics, troubleshooting skills, and a strong publication record. Experience in enzyme engineering, molecular dynamics, and programming is preferred.
You will co-design protein engineering efforts, use deep learning for predictive modeling, analyze biochemical data, collaborate with a multidisciplinary team, communicate results effectively, and author publications.

Requirements

Must be a recent PhD graduate within the last three years.* Must meet educational requirements prior to employment start date.
Additional Required Qualifications:
Research experience in machine learning, deep learning, and bioinformatics
Troubleshooting skills, problem-solving skills, and attention to detail
Ability to deliver high-quality results within aggressive timelines
A strong publication history in the peer-reviewed scientific literature
Preferred Qualifications:
Experience developing approaches to select for and engineer thermo-tolerant enzymes
Relevant experience with molecular dynamics simulations
Demonstrated experience in Python and/or other relevant programming languages, especially applied to the development of high-throughput computational workflows

Responsibilities

co-design the planning and execution of protein selection, design, and engineering efforts with other researchers
use state-of-the-art deep learning methods to develop predictive models with applications in enzyme selection, engineering, and design
use machine learning techniques to analyze biochemical data to make engineering recommendations for improving desired enzyme properties
work with small experimental datasets, using techniques such as semi-supervised learning, transfer learning, etc.
use structural information, bioinformatics, molecular modeling, and / or machine learning techniques to develop protein sequence/structure/function relationships and make engineering recommendations for improving desired enzyme properties
work effectively both independently and in a large, multidisciplinary, multi-institutional team of biologists, chemists, and engineers.
collaborate with modeling and experimental collaborators to plan, execute, discuss, and analyze project results and propose new directions.
communicate scientific results effectively, both in written and oral formats
author peer-reviewed publications
maintain professionalism and an environment of mutual respect in all communication and interactions with fellow staff and collaborators

FAQs

What kind of research will the postdoctoral researcher be focused on?

The postdoctoral researcher will focus on developing machine learning and deep learning tools to identify and design enzymes for various applications related to renewable energy and materials for a circular economy.

What are some specific areas of focus for the research?

The research will specifically focus on enzyme design for deconstruction of polymer waste, conversion of C1 substrates, biosensor design, and metabolic pathway optimization.

Will the postdoctoral researcher work independently or as part of a team?

The postdoctoral researcher will work in close collaboration with a large, multi-disciplinary, multi-institutional team.

What is the goal of the research being conducted by the Renewable Resources and Enabling Sciences Center?

The goal of the research is to develop innovative approaches to renewable energy and materials for a circular economy through biological, chemical, and catalytic research.

How can interested candidates apply for the postdoctoral researcher position?

Interested candidates can apply for the position through NREL's job posting website or through other relevant channels as specified by the institution.

National Renewable Energy Laboratory

Science & Healthcare

Industry

1001-5000

Employees

1977

Founded Year

Mission & Purpose

The National Renewable Energy Laboratory (NREL), a Department of Energy national lab, is #TransformingEnergy as the nation's primary laboratory for renewable energy and energy efficiency research and development. NREL's Mission: NREL develops renewable energy and energy efficiency technologies and practices, advances related science and engineering, and transfers knowledge and innovations to address the nation's energy and environmental goals. NREL's Strategy: NREL has forged a focused strategic direction to increase its impact on the U.S. Department of Energy's (DOE) and our nation's energy goals by accelerating the research path from scientific innovations to market-viable alternative energy solutions.