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Senior Scientist, Chemistry

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Bristol Myers Squibb

26d ago

  • Job
    Full-time
    Mid, Senior & Expert Level
  • Science
    Research & Development
  • San Diego

AI generated summary

  • You should have a PhD in chemistry (or BS with 15+ years), experience in cancer therapies, strong problem-solving skills, data sharing ability, and proven leadership in drug discovery.
  • You will design and synthesize compounds, support SAR campaigns, collaborate with interdisciplinary teams, supervise junior scientists, and contribute to publications while ensuring safety and quality.

Requirements

  • PhD in synthetic organic, peptide or medicinal chemistry with 4 + years of post-PhD/postdoc experience or BS with 15+ years experience in Pharmaceutical/biotech R&D environments demonstrating successful accomplishments and productivity.
  • Experience in working on targeted cancer therapy modalities such as RPTs, ADCs, PDCs is highly desirable.
  • Well versed in modern synthetic organic/peptide/med chem principles and demonstrated track record of high productivity and achievements in the lab.
  • High scientific curiosity and a learning mindset coupled with strong technical problem-solving skills and strong understanding of the concepts of drug design, SAR analysis, ADME/PK is important.
  • The ability to share data and collaborate with cross functional team members is critical as is the ability to effectively interpret data and plan experiments without supervision.
  • Excellent written and oral communication and presentation skills and ability to work in a fast-paced, dynamic, and collaborative environment.
  • Demonstrated ability to supervise and effectively guide the work of junior scientists and demonstrated ability of productivity in an industrial drug discovery setting.

Responsibilities

  • Design and synthesize novel peptide/small molecule compounds in support of SAR campaigns for pipeline projects.
  • Contribute towards developing SAR on assigned projects, design and synthesize key target molecules to assess chemical/biological hypothesis.
  • Independently plan and execute organic synthesis routes for complex molecules. Utilize modern purification and analytical tools to support synthesis and characterization of target compounds.
  • Work in close collaboration with interdisciplinary team members to provide needed chemistry support to guide programs through lead identification/optimization phases.
  • Work closely with chemists, DMPK, imaging and in vitro/vivo teams to ensure that target compounds are generated in a timely manner to support the screening funnel.
  • Contribute experimental efforts in support of target selection and initiation of new TRP projects.
  • Keep abreast of the literature in the field of RPTs, identify novel concepts and ideas to help advance the state of art in RPT field.
  • Contribute towards IP filings and drafting of publications, presentations.
  • Routinely present research findings, project updates in interdisciplinary team settings.
  • Adhere rigorously to safety guidelines, regulatory standards and company policies and ensure a safe working environment.
  • Identify external partners, KOLs, outside expertise that will help advance the pipeline.
  • Supervise the work of junior scientists and ensure experimental rigor and high quality.

FAQs

What is the primary focus of RayzeBio, a Bristol Myers Squibb company?

RayzeBio is focused on improving survival rates for people with cancer by developing innovative drugs against targets of solid tumors, specifically utilizing the power of targeted radioisotopes.

What qualifications are required for the Senior Scientist position?

Candidates should have a PhD in synthetic organic, peptide, or medicinal chemistry with at least 4 years of post-PhD/postdoc experience, or a BS with 15+ years of experience in Pharmaceutical/biotech R&D environments.

What are the key responsibilities of the Senior Scientist role?

Key responsibilities include designing and synthesizing novel peptide/small molecule compounds, contributing to SAR campaigns, planning and executing organic synthesis routes, collaborating with interdisciplinary teams, and supervising junior scientists.

Is prior experience in targeted cancer therapy modalities necessary?

Yes, experience in targeted cancer therapy modalities such as RPTs, ADCs, and PDCs is highly desirable.

What essential skills should a candidate possess for this position?

Candidates should be well-versed in modern synthetic organic/peptide/med chem principles, possess strong technical problem-solving skills, exhibit excellent written and oral communication skills, and have the ability to collaborate effectively with cross-functional teams.

What is the compensation range for this position?

The starting compensation for this job ranges from $127,211 to $172,109, plus incentive cash and stock opportunities, based on eligibility and individual experience.

Does this role require in-office work?

Yes, this position is site-essential, meaning that it requires 100% of shifts to be conducted onsite at the assigned facility.

What should I do if I need reasonable accommodations during the recruitment process?

Applicants can request reasonable workplace accommodations or adjustments by directing their inquiries to adastaffingsupport@bms.com prior to accepting a job offer.

What is BMS’s stance on COVID-19 vaccinations for employees?

BMS strongly recommends that all employees be fully vaccinated for COVID-19 and keep up to date with COVID-19 boosters to ensure the well-being of staff and the wider community.

How does BMS promote diversity within the workplace?

BMS promotes diversity through an inclusive culture where every employee is empowered to apply their unique perspectives, thereby enhancing innovation and collaboration.

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Bristol Myers Squibb

Manufacturing & Electronics
Industry
10,001+
Employees

Mission & Purpose

At Bristol Myers Squibb, we work every day to transform patients’ lives through science. That work inspires some of the most interesting, meaningful, and life-changing careers you’ll experience. Join us and pursue innovative ideas alongside some of the brightest minds in biopharma, collaborating with a team rich in diversity of experiences, and perspectives. We have built a sustainable pipeline of potential therapies and are leveraging translational medicine and data analytics to understand how we can deliver the right medicine to the right patient, at the right time, to achieve the best outcome. Whether in a scientific, business or supporting function, a career at BMS means you’ll be inspired every day to grow and thrive through opportunities that are uncommon in scale and scope. Here, you’ll be on the cutting edge of powerful innovation in oncology, hematology, immunology, cardiovascular disease, and fibrosis, with colleagues united in the mission to help patients. Through the Bristol Myers Squibb Foundation, we also promote health equity and seek to improve health outcomes of populations disproportionately affected by serious diseases and conditions. Our mission is to give new hope to help patients prevail over serious disease – it drives everything we do.