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PhD Student in Metabolomics

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Vrije Universiteit Amsterdam (VU Amsterdam)

6d ago

  • Job
    Full-time
    Entry Level
  • Research & Development
  • Amsterdam
  • 25d left

AI generated summary

  • You need a Master’s in Biochemistry or related field, interest in metabolomics, HPLC/MS/NMR experience, some programming skills, strong communication, team spirit, and motivation for research.
  • You will develop metabolomics workflows, cultivate microbial cultures, implement sample preparation, interpret data, collaborate with teams, and publish research findings.

Requirements

  • Master degree in Biochemistry, Analytical Chemistry, Chemistry, or a related discipline;
  • Strong interest in metabolism, metabolomics, and pathway analysis;
  • Previous experience in handling HPLC, MS or NMR techniques will be considered as an asset;
  • Programming knowledge (R, Python, MATLAB) may be an advantage;
  • Strong communication, organizational and social skills;
  • Fluent in speaking and writing English;
  • Team player with the ability to work independently;
  • Strong motivation for scientific research.

Responsibilities

  • Develop metabolomics workflows (based on liquid chromatography mass spectrometry, LC-MS, and nuclear magnetic resonance, NMR) from sample production to metabolic networks and interpretation;
  • Cultivation of microbial cultures to study metabolism of plant substrates;
  • Implement sample preparation strategies to monitor intracellular and extracellular metabolome;
  • Develop metabolomics methods that elucidate metabolic pathways associated with catabolism of plant secondary metabolites;
  • Interpret and integrate metabolism readouts with functional assays (e.g. growth curves and other omics);
  • Contribute and collaborate with others in data integration;
  • Conduct research within the scope of the project leading to a dissertation;
  • Publish scientific articles and present research results at conferences;
  • Collaborate within the team, with the FERMI consortium, and with other international researchers.

FAQs

What is the primary focus of the PhD project?

The primary focus of the PhD project is to develop metabolomics workflows to study the metabolic changes observed through the fermentation of plant substrates, with the aim of improving plant-based food alternatives.

What qualifications are required for this position?

A Master’s degree in Biochemistry, Analytical Chemistry, Chemistry, or a related discipline is required, along with a strong interest in metabolism, metabolomics, and pathway analysis.

Is previous experience with LC-MS or NMR techniques necessary?

While not strictly necessary, previous experience in handling HPLC, MS, or NMR techniques will be considered an asset.

Are there opportunities for collaboration in this role?

Yes, the position offers opportunities to collaborate within the team, with the FERMI consortium, and with other international researchers.

What are the main duties of the PhD student?

The main duties include developing metabolomics workflows, cultivating microbial cultures, implementing sample preparation strategies, elucidating metabolic pathways, integrating data, conducting research leading to a dissertation, publishing scientific articles, and presenting at conferences.

What languages need to be spoken and written fluently?

Fluency in English, both spoken and written, is required for this position.

What type of employment contract is offered?

An initial employment contract of 1 year is offered, with the possibility of extension to a total of 4 years if there is sufficient perspective.

What is the salary range for the PhD position?

The salary ranges from €2,872.00 for the first year to a maximum of €3,670.00 in the fourth year (PhD).

How many hours constitute a full-time working week in this position?

A full-time working week consists of 38 hours, granting a holiday leave entitlement of 232 hours per year.

Are there initiatives in place for diversity and inclusion?

Yes, the university is committed to creating an inclusive community and values diversity in numerous aspects, recognizing it as an asset for quality teaching, research, and service.

Vrije Universiteit Amsterdam (VU Amsterdam)

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