You need an upper 2nd or 1st class honours in Physics, Chemistry, Materials Science, or Maths, programming experience, and industry engagement for this PhD studentship at the University of Cambridge.

You will develop a model to predict tablet compression behaviors, applying it to upscale tablet production studies at the University of Cambridge.

Science

Engineering

United Kingdom

Cambridge

Large

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<ul><li><span style="background-color: rgb(255, 255, 255); color: rgb(68, 68, 68);">During early-stage formulation and process development, scientists undergo extensive experimental screening campaigns and, although the tablet failure risk is reduced, there still exist risks that remain undetected and often cause issues during upscaling to production settings, leading to delays and at times undesired process changes. Being able to predict the compaction behaviour at different compression speeds, densities and compositions before formulations are transferred to large-scale production, will be a game changer in the tabletting field. Develop an experimental protocol to investigate the effect of the compression speed, tablet composition and powder characteristics on the tabletting performance.</span></li></ul>

During early-stage formulation and process development, scientists undergo extensive experimental screening campaigns and, although the tablet failure risk is reduced, there still exist risks that remain undetected and often cause issues during upscaling to production settings, leading to delays and at times undesired process changes. Being able to predict the compaction behaviour at different compression speeds, densities and compositions before formulations are transferred to large-scale production, will be a game changer in the tabletting field. Develop an experimental protocol to investigate the effect of the compression speed, tablet composition and powder characteristics on the tabletting performance.

PhD Studentship: Modelling of strain-rate effects in pharmaceutical tabletting

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University of Cambridge

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