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Job

PhD Studentship: Modelling of strain-rate effects in pharmaceutical tabletting

💼 Graduate Job

Cambridge

🤑 £19.3K
⌛ Closed
Applications are closed

Graduate Job

Science, Engineering•Cambridge

Description

  • During early-stage formulation and process development, scientists undergo extensive experimental screening campaigns and, although the tablet failure risk is reduced, there still exist risks that remain undetected and often cause issues during upscaling to production settings, leading to delays and at times undesired process changes. Being able to predict the compaction behaviour at different compression speeds, densities and compositions before formulations are transferred to large-scale production, will be a game changer in the tabletting field. Develop an experimental protocol to investigate the effect of the compression speed, tablet composition and powder characteristics on the tabletting performance.

Requirements

  • Applicants should have (or expect to be awarded) an upper 2nd or 1st class honours degree at the level of MSci, MEng (or overseas equivalents) in a relevant subject (Physics, Chemistry, Materials Science, Maths), some programming experience and a willingness to engage with industry throughout the project.

Education requirements

PhD

Area of Responsibilities

Science
Engineering

Responsibilities

  • The main aims of this project are:
  • Improve our existing discrete element model ((VLS-DEM) to enable the compression performance prediction considering the attributes mentioned above.
  • Apply the framework to a systematic tablet production upscaling study.

Details

Work type

Full time

Work mode

office

Application deadline

May 16, 2024

Location

Cambridge

Salary

19327 GBP